Henningsen Peter, Löwe Bernd
Department of Psychosomatic Medicine, University Hospital, Technical University Munich, Germany.
Curr Opin Psychiatry. 2006 Jan;19(1):19-24. doi: 10.1097/01.yco.0000189880.11059.8d.
The frequent co-occurrence of depression and somatic symptoms poses a continuing challenge to clinicians, researchers and experts involved in drawing up classifications. In this review we present recently published literature on aspects of epidemiology, classification and treatment in this important overlap area.
From the multitude of papers published annually on the co-occurrence of different pain conditions and depression, temporomandibular dysfunction stands out this year by sheer quantity; it can be seen as a model case of the necessity for differentiated high-quality assessments on the biological as well as the psychosocial level. There is a general move to separate utility of diagnostic classifications from their validity, and this strengthens classificatory approaches that help to view the regular overlap of depression, pain and other somatic symptoms as the rule rather than the exception. The incorporation of cognitive variables like causal attributions should help to distinguish clinically relevant subtypes among overlap cases. The classificatory future of the category of 'somatoform disorders' is somewhat in doubt, but reforms seem to be more productive than abolishment. Psychopharmacology provides rather intense recent coverage of the overlap field, with newer dual serotonergic-noradrenergic reuptake inhibitors offering some promise.
Treating the overlap of depression, pain and other somatic symptoms as the rule rather than the exception is necessary for adequate aetiological research as well as for diagnosis and treatment, with one-dimensional classificatory and treatment approaches almost certainly being insufficient.
抑郁症与躯体症状经常同时出现,这给参与制定分类的临床医生、研究人员和专家带来了持续的挑战。在本综述中,我们展示了最近发表的关于这一重要重叠领域的流行病学、分类和治疗方面的文献。
在每年发表的众多关于不同疼痛状况与抑郁症同时出现的论文中,颞下颌关节功能紊乱症今年因其数量之多而格外突出;它可被视为在生物学和心理社会层面进行高质量差异化评估必要性的一个典型案例。目前普遍倾向于将诊断分类的实用性与有效性区分开来,这强化了分类方法,有助于将抑郁症、疼痛和其他躯体症状的常规重叠视为常态而非例外。纳入因果归因等认知变量应有助于在重叠病例中区分出临床相关的亚型。“躯体形式障碍”这一类别在分类学上的未来有些不确定,但改革似乎比废除更有成效。心理药理学最近对重叠领域的报道相当密集,新型的血清素 - 去甲肾上腺素再摄取双重抑制剂显示出一些前景。
将抑郁症、疼痛和其他躯体症状的重叠视为常态而非例外,对于充分的病因学研究以及诊断和治疗都是必要的,一维的分类和治疗方法几乎肯定是不够的。