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[经颅磁刺激在神经心理学中的应用:大脑研究的新视野]

[Transcranial magnetic stimulation in neuropsychology: new horizons for brain research].

作者信息

Boggio Paulo Sérgio, Fregni Felipe, Rigonatti Sérgio Paulo, Marcolin Marco Antônio, Silva Maria Teresa Araujo

机构信息

Departamento de Psicologia Experimental, Instituto de Psicologia, Universidade de São Paulo, São Paulo, SP, Brazil.

出版信息

Braz J Psychiatry. 2006 Mar;28(1):44-9. doi: 10.1590/s1516-44462006000100010. Epub 2006 Mar 24.

Abstract

This review addresses the use of transcranial magnetic stimulation as a research tool of neuropsychological functions. Transcranial magnetic stimulation is a non-invasive and painless technique to modulate brain function that can be applied to conscious human beings and is based on a variable magnetic field. Using this technique, it is possible to generate virtual transient lesions in healthy people or modulate the brain activity, increasing or decreasing the activity of the stimulated areas. In this review we discuss studies with transcranial magnetic stimulation in which broad aspects of language, memory and neuropsychological tests have been evaluated following or during the application of transcranial magnetic stimulation. We concluded that transcranial magnetic stimulation open new horizons for brain research in the neuropsychological field as transcranial magnetic stimulation allows the investigation of the relationship between focal cortical activity and behavior therefore contributing to the study of the functional brain activity.

摘要

本综述探讨了经颅磁刺激作为神经心理功能研究工具的应用。经颅磁刺激是一种非侵入性且无痛的调节脑功能技术,可应用于清醒的人类,基于可变磁场。使用该技术,能够在健康人身上产生虚拟短暂性损伤或调节脑活动,增加或减少受刺激区域的活动。在本综述中,我们讨论了经颅磁刺激的相关研究,其中在经颅磁刺激应用之后或期间,对语言、记忆和神经心理测试的广泛方面进行了评估。我们得出结论,经颅磁刺激为神经心理领域的脑研究开辟了新视野,因为经颅磁刺激能够研究局灶性皮质活动与行为之间的关系,从而有助于对功能性脑活动的研究。

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