Schneider K, Hrasky A, Aschoff P, Bihl H, Hagen R
Klinik für Hals-Nasen-Ohren-Krankheiten, Plastische Operationen, Klinikum Stuttgart, Katharinenhospital.
Laryngorhinootologie. 2006 Nov;85(11):819-23. doi: 10.1055/s-2006-925297. Epub 2006 Apr 10.
In the last years (18)F-FDG-positron-emission-tomography (PET) worked satisfactorily as helpful auxiliary method in order to verify recurrency of head and neck tumors and to detect primary tumors in case of CUP syndrome especially when CT and MR imaging failed to identify the tumor accurately. Fusion of FDG hypermetabolism in PET scan and anatomical structures is achieved by integrating positron emission tomography with CT and provides improvement also in case of CUP syndrome. This retrospective study shows 47 patients with neck metastases where PET or PET/CT helped to detect primary tumor site.
In a retrospective investigation 49 PET studies of 47 patients with CUP syndrome were analyzed.
9 cases had positive PET findings, 1 case false-positive. 5 cases were false-negative. In 40 PET studies there couldn't be found any sign of suspicious FDG hypermetabolism.
PET and PET/CT deliver a certain improvement in localization of primary tumor site and therapeutical strategy.
在过去几年中，（18）F - 氟代脱氧葡萄糖正电子发射断层扫描（PET）作为一种有用的辅助方法，在验证头颈部肿瘤复发以及在不明原发癌（CUP）综合征情况下检测原发肿瘤方面表现令人满意，尤其是当CT和磁共振成像（MR）无法准确识别肿瘤时。通过将正电子发射断层扫描与CT相结合，可实现PET扫描中FDG高代谢与解剖结构的融合，在CUP综合征情况下也能提供帮助。这项回顾性研究展示了47例颈部转移患者，其中PET或PET/CT有助于检测原发肿瘤部位。
在一项回顾性调查中，分析了47例CUP综合征患者的49次PET检查。
9例PET检查结果为阳性，1例假阳性。5例假阴性。在40次PET检查中未发现任何可疑的FDG高代谢迹象。
PET和PET/CT在原发肿瘤部位定位和治疗策略方面有一定改善。
