Schneider K, Aschoff Ph, Bihl H, Hagen R
Klinik für Hals-Nasen-Ohren-Krankheiten, Plastische Operationen, Klinikum Stuttgart, Katharinenhospital.
Laryngorhinootologie. 2006 Mar;85(3):179-83. doi: 10.1055/s-2005-870509.
In the last years (18)F-Fluoro-deoxy-glucose (FDG)-positron emission tomography (PET) worked satisfactorily as auxiliary method in order to show recurrency of head and neck tumors and to detect primary tumors in case of CUP especially when CT and MR imaging failed to identify the tumor accurately. The correlation of FDG hypermetabolism and anatomical structures is now provided by a new technology which is integrating PET and CT: Integrated PET/CT represents a new technical development, which combines the advantages of CT and PET.
In a retrospective investigation 84 non selected PET/CT studies of 83 patients with recurrent head and neck disease and CUP were critically analyzed.
33 cases had positive PET findings. 5 of these 33 cases showed false-positive findings. In 51 PET studies there was not found any sign of suspicious FDG hypermetabolism.
Integrated PET/CT delivers substantial progress in detecting tumor localization. False positive findings have to be considered and therefore indications should be strictly limited to special cases of head and neck tumor recurrency, cases with complex anatomical sites and CUP.
在过去几年中，（18）F-氟脱氧葡萄糖（FDG）正电子发射断层扫描（PET）作为一种辅助方法，在显示头颈部肿瘤复发以及在不明原发灶（CUP）情况下检测原发肿瘤方面表现良好，尤其是当CT和磁共振成像（MR）无法准确识别肿瘤时。一种将PET和CT整合的新技术现在提供了FDG高代谢与解剖结构的相关性：一体化PET/CT代表了一项新的技术发展，它结合了CT和PET的优势。
在一项回顾性研究中，对83例复发性头颈部疾病和不明原发灶患者的84项未选择的PET/CT研究进行了严格分析。
33例PET检查结果为阳性。这33例中有5例显示假阳性结果。在51项PET研究中，未发现任何可疑的FDG高代谢迹象。
一体化PET/CT在检测肿瘤定位方面取得了重大进展。必须考虑假阳性结果，因此适应症应严格限于头颈部肿瘤复发的特殊情况、解剖部位复杂的病例和不明原发灶病例。
