Kawamura Masaki, Daida Hiroyuki
Department of Cardiology, Juntendo University Shizuoka Hospital.
Nihon Rinsho. 2006 Apr;64(4):788-93.
Recent advances in thrombolytic therapy and percutaneous coronary intervention (PCI) have resulted in dramatic improvements in the outcome of patients with acute coronary syndromes (ACS). Unfortunately, the reduced risk of cardiac and non-cardiac complications associated with advancements in technology has also been paralleled by an increase in the incidence of some complications. The most important complications relate to abrupt vessel closure with PCI, which may result in myocardial infarction or cardiac death. Major bleeding is also a relatively frequent non-cardiac complication of thrombolytic therapy and it is associated with a poor hospital prognosis. Most complication can be prevented or at least minimized with proper strategy, execution, and patient selection.
溶栓治疗和经皮冠状动脉介入治疗（PCI）的最新进展已使急性冠状动脉综合征（ACS）患者的治疗结果得到显著改善。不幸的是，技术进步带来的心脏和非心脏并发症风险降低的同时，一些并发症的发生率也有所增加。最重要的并发症与PCI术中血管突然闭塞有关，这可能导致心肌梗死或心源性死亡。大出血也是溶栓治疗相对常见的非心脏并发症，且与不良的住院预后相关。通过适当的策略、实施和患者选择，大多数并发症是可以预防的，或者至少可以将其影响降至最低。
