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[前庭神经鞘瘤伴脑积水病例,经肿瘤切除治疗]

[Case of hydrocephalus associated with vestibular schwannoma, treated by tumor removal].

作者信息

Kanayama Seisaku, Kohno Michihiro, Okamura Kohichi, Yoshino Masanori, Segawa Hiroshi, Saito Isamu, Sano Keiji

机构信息

Department of Neurosurgery, Fuji Brain Institute and Hospital, 270-12 Sugita, Fujinomiya-shi, Shizuoka 418-0021, Japan.

出版信息

No Shinkei Geka. 2006 Apr;34(4):391-5.

Abstract

A 57-year-old male presented with gait disturbance, urinary incontinence, dementia resembling symptom of normal pressure hydrocephalus (NPH) and was admitted to our institusion. A computerized tomographic scan (CT) and magnetic resonance imaging (MRI) revealed hydrocephalus as well as a tumor in the right cerebellopontine angle. We diagnosed communicating-type hydrocephalus associated with the vestibular schwannoma and tumor removal was performed prior to ventriculo-peritoneal (V-P) shunt. After surgery, symptoms of the patient disappeared promptly and cerebrospinal fluid protein elevation was normalized. One month after surgery, CT and MRI revealed reduction of the ventricle size and V-P shunt became unnecessary. Hydrocephalus is occasionally complicated by vestibular schwannoma. The majority results from obstruction of the cerebrospinal fluid (CSF) pathway by large tumors. But, small tumors also cause communicating-type hydrocephalus. Although the selection of the treatment is controversial, tumor removal without a shunt is considered as a good strategy for management of hydrocephalus associated with vestibular schwannoma.

摘要

一名57岁男性因步态障碍、尿失禁、类似正常压力脑积水(NPH)的痴呆症状入院。计算机断层扫描(CT)和磁共振成像(MRI)显示脑积水以及右侧桥小脑角肿瘤。我们诊断为与前庭神经鞘瘤相关的交通性脑积水,并在脑室-腹腔(V-P)分流术前进行了肿瘤切除。术后,患者症状迅速消失,脑脊液蛋白升高恢复正常。术后1个月,CT和MRI显示脑室大小缩小,无需进行V-P分流。脑积水偶尔会并发前庭神经鞘瘤。大多数情况是由大肿瘤阻塞脑脊液(CSF)通路所致。但是,小肿瘤也会导致交通性脑积水。尽管治疗方法的选择存在争议,但不进行分流的肿瘤切除被认为是治疗与前庭神经鞘瘤相关脑积水的良好策略。

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