Smalley K S M, Herlyn M
The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA.
Mini Rev Med Chem. 2006 Apr;6(4):387-93. doi: 10.2174/138955706776361402.
Novel anti-cancer treatments use knowledge about the underlying biology of the tumor to find suitable molecular targets. The recent years have seen great advances in understanding the biology of melanoma. In the current review we discuss the most promising molecular targets for melanoma and suggest possible strategies for overcoming resistance.
新型抗癌疗法利用有关肿瘤潜在生物学特性的知识来寻找合适的分子靶点。近年来，在黑色素瘤生物学特性的理解方面取得了巨大进展。在本综述中，我们讨论了黑色素瘤最有前景的分子靶点，并提出了克服耐药性的可能策略。
