Venelinov Tony, Arpadjan Sonia, Karadjova Irina, Beattie John
Sofia University, Faculty of Chemistry, Department of Analytical Chemistry, 1164 Sofia, Bulgaria.
Acta Pharm. 2006 Mar;56(1):105-12.
The copper(II)-histidine complex obtained following dialysis of human plasma with histidine was investigated using various types of extraction systems and ion exchange resins. According to the results obtained, the Cu(II)-histidine complex formed under the dialysis conditions has one positive charge. Preconcentration of copper from the dialysis solution was achieved by its extraction as a dithiocarbamate complex and by sorption on cation-exchange resin or onto chelate sorbent.
用组氨酸对人血浆进行透析后得到的铜（II）-组氨酸络合物，通过各种萃取系统和离子交换树脂进行了研究。根据所得结果，在透析条件下形成的铜（II）-组氨酸络合物带一个正电荷。通过将其作为二硫代氨基甲酸盐络合物萃取以及吸附在阳离子交换树脂或螯合吸附剂上，实现了从透析液中预富集铜。
