Arceci F, Falzoni P, Giorgione R, Rudoni M, Tragni G, Montino F, Poletti C, Robecchi A
III Clinica Chirurgica, Università di Torino, Ospedale Maggiore della Carità, Novara.
Minerva Chir. 1991 Aug;46(15-16):799-804.
In order to evaluate the clinical utility of autologous splenic transplantation in the omental pouch, a pneumococcal challenge was performed in 3 groups of rats, after demonstration of vitality of the intraperitoneal inoculum: Group A: splenectomized rats; Group B: reimplanted rats; Group C: sham operation. No statistically significant difference was found between the first two groups regarding resistance against infection (p less than 0.982), while normal rats proved more resistant (p less than 0.031). Between group A and B significant differences (p less than 0.001) exists only for a more precocious mortality in the first group. The poor clinical utility of the technique is demonstrated.
为了评估自体脾移植至网膜囊的临床效用，在证实腹腔接种物具有活力后，对三组大鼠进行了肺炎球菌攻击试验：A组：脾切除大鼠；B组：脾再植大鼠；C组：假手术组。在前两组之间，就抗感染能力而言未发现统计学上的显著差异（p小于0.982），而正常大鼠表现出更强的抗感染能力（p小于0.031）。A组和B组之间仅在第一组出现更早死亡方面存在显著差异（p小于0.001）。该技术的临床效用不佳得到了证实。
