Jalenques I, Coudert A J
Service de psychiatrie A, groupe hospitalier Saint-Jacques, Clermont-Ferrand, France.
Pediatrie. 1991;46(11):743-50.
Anxiety and depression are often clinically associated in children, but are very different in term of effect and symptoms. Family studies favor the hypothesis of a common diathesis for these disorders. Parental history of major depressive and/or anxiety disorders increase the risk of mood and anxiety disorders in children. At the present time, biological studies have not determined any biochemical conclusion for these disorders. It should be noted that although imipramine is efficient in both depressive disorder and separation anxiety, this does not implicate a common physiopathologic basis.
焦虑和抑郁在临床上常与儿童相关联,但在影响和症状方面却大不相同。家族研究支持这些疾病存在共同素质的假说。父母有重度抑郁和/或焦虑症病史会增加孩子患情绪和焦虑症的风险。目前,生物学研究尚未确定这些疾病的任何生化结论。应当指出的是,尽管丙咪嗪对抑郁症和分离焦虑症都有效,但这并不意味着存在共同的生理病理基础。