Claris O, Gay C, Putet G, Salle B L
Service de pathologie et de réanimation néonatale, hôpital Edouard-Herriot, Lyon, France.
Pediatrie. 1991;46(11):751-6.
Neonatal mortality and morbidity were reported over a 4-yr period from 1986-1989 in premature infants weighing less than 1,500 g, 278 of whom were born in the same obstetrico-neonatal unit. Total mortality was 15%, and was higher in premature infants weighing less than 1,000 g (38%) and lower if the gestational age was greater than 27 wk. Mortality was lower in small for gestational age (SGA) infants than in appropriate for gestational age (AGA) infants (5% vs 19%, P less than 0.001), and lower in inborn babies than in outborn (12% vs 19%, P less than 0.02) but only in neonates weighing less than 1,000 g. Neonatal morbidity was mainly due to hyaline membrane disease and cerebral haemorrhage. The incidence of broncho-pulmonary dysplasia was low (4%). These results indicate that gestational age, birth weight and place of delivery play a role in mortality and morbidity in very low birth weight premature infants.
1986年至1989年的4年期间，对体重不足1500克的早产儿的新生儿死亡率和发病率进行了报告，其中278例出生于同一产科新生儿病房。总死亡率为15%，体重不足1000克的早产儿死亡率更高（38%），而胎龄大于27周的早产儿死亡率较低。小于胎龄（SGA）婴儿的死亡率低于适于胎龄（AGA）婴儿（5%对19%，P<0.001），且足月儿的死亡率低于早产儿（12%对19%，P<0.02），但仅适用于体重不足1000克的新生儿。新生儿发病主要归因于肺透明膜病和脑出血。支气管肺发育不良的发生率较低（4%）。这些结果表明，胎龄、出生体重和分娩地点在极低出生体重早产儿的死亡率和发病率中起作用。
