Mikhail G W
Imperial College London, The North West London Hospitals Trust, London, UK.
Heart. 2006 May;92 Suppl 3(Suppl 3):iii19-23. doi: 10.1136/hrt.2005.070359.
Coronary heart disease is the leading cause of death in men and women worldwide. It is still considered a disease of men and there has been little recognition of its importance in women. Gender differences exist in acute and chronic ischaemia in terms of clinical manifestations, investigations and treatment. There are clear gender differences in coronary revascularisation with a higher mortality seen in women. At the time a woman presents with coronary artery disease she is older and has more co-morbid factors. Furthermore, women have smaller coronary arteries making them more difficult to revascularise. In recent years there has been a general trend towards improved outcomes in women undergoing both surgical and percutaneous coronary intervention. The increasing use of drug eluting stents and adjunctive medical treatment as well as the use of off-pump bypass surgery needs further evaluation in terms of gender differences. This article reviews the current literature on coronary revascularisation in women.
冠心病是全球男性和女性的主要死因。它仍被视为男性疾病，其在女性中的重要性几乎未得到认可。在急性和慢性缺血方面，男女在临床表现、检查和治疗上存在性别差异。在冠状动脉血运重建方面存在明显的性别差异，女性的死亡率更高。当女性出现冠状动脉疾病时，其年龄更大且合并症更多。此外，女性的冠状动脉更细，使其血运重建更加困难。近年来，接受外科和经皮冠状动脉介入治疗的女性患者的治疗效果总体呈改善趋势。药物洗脱支架和辅助药物治疗的日益广泛应用以及非体外循环搭桥手术的使用，在性别差异方面需要进一步评估。本文综述了有关女性冠状动脉血运重建的当前文献。
