Aublin P C, Aublin C
Rev Fr Gynecol Obstet. 1991 Jul-Sep;86(7-9):515-21.
With the current development of mammographic screening of women over 50 years of age, there is a 7 percent increase in the number of cases of in situ canalar cancer; in some studies, this increase is a high as 15 or 20 percent. This cancer raises two types of problem. First, histologically, a large number of varieties have been identified and it is difficult for histologists to study the basal form in its integrity. Second, on the therapeutic level, there is disagreement as to the choice of limited surgery and mastectomy with or without radiotherapy. Unfortunately, one characteristic of in situ cancer is that it tends to recur in an invasive form or in situ.
随着目前对50岁以上女性进行乳腺钼靶筛查的开展，原位管癌的病例数增加了7%；在一些研究中，这一增幅高达15%或20%。这种癌症引发了两类问题。首先，在组织学上，已识别出大量变体，组织学家很难完整地研究其基础形态。其次，在治疗层面，对于选择有限手术以及是否进行放疗的乳房切除术存在分歧。不幸的是，原位癌的一个特点是它往往会以浸润性形式或原位复发。
