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[抗肿瘤坏死因子α在银屑病关节炎治疗中的应用]

[Anti-TNF alpha in the treatment of psoriatic arthritis].

作者信息

Claudepierre Pascal, Wendling Daniel, Cohen Jean-David

机构信息

Service de Rhumatologie, CHU Henri Mondor, Créteil.

出版信息

Presse Med. 2006 Apr;35(4 Pt 2):647-55. doi: 10.1016/s0755-4982(06)74658-9.

Abstract

Psoriatic arthritis is an inflammatory and possibly destructive form of arthritis. As in rheumatoid arthritis and ankylosing spondylitis, the use of biological therapy in psoriatic arthritis is a therapeutic revolution: both articular and cutaneous efficacy have been shown, and some improvement is visible on radiography. The benefit-risk ratio will improve when we learn to identify more accurately the patients likely to benefit from these treatments.

摘要

银屑病关节炎是一种炎症性且可能具有破坏性的关节炎形式。与类风湿关节炎和强直性脊柱炎一样,生物疗法在银屑病关节炎治疗中的应用是一场治疗革命:已证实其在关节和皮肤方面均有疗效,并且在放射影像学上也可见到一些改善。当我们学会更准确地识别可能从这些治疗中获益的患者时,其效益风险比将会得到改善。

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