Schuurmans Mascha, Vanneste Jan A L, Verstegen Marco J T, van Furth Wouter R
Department of Neurology, Sint Lucas Andreas Ziekenhuis, Amsterdam, The Netherlands.
J Neurooncol. 2006 Aug;79(1):57-9. doi: 10.1007/s11060-005-9114-9. Epub 2006 Apr 14.
We describe a 29-year-old woman who presented with progressive neck pain, sensory deficit and weakness in both arms. Magnetic resonance imaging (MRI) of the cervical spine revealed an extramedullary tumor with severe spinal cord compression. During surgery an intradural extramedullary tumor was found. Further imaging showed a second lumbar spinal tumor. Microscopy of both tumors showed that both tumors were anaplastic ependymomas, which almost never present as extramedullary tumors. Two years after surgery, an intracranial extracerebral metastasis was found, without evidence of spinal recurrence.
我们描述了一位29岁女性,她出现进行性颈部疼痛、感觉障碍和双臂无力。颈椎磁共振成像(MRI)显示髓外肿瘤伴严重脊髓受压。手术中发现硬膜内髓外肿瘤。进一步影像学检查显示第二腰椎脊髓肿瘤。两个肿瘤的显微镜检查表明,这两个肿瘤均为间变性室管膜瘤,几乎从未表现为髓外肿瘤。手术后两年,发现颅内脑外转移,无脊髓复发证据。