减数分裂染色体花束：SUN蛋白收集“花朵”。

The meiotic chromosomal bouquet: SUN collects flowers.

作者信息

Tomita Kazunori, Cooper Julia Promisel

机构信息

Telomere Biology Laboratory, Cancer Research UK, London WC2A 3PX, United Kingdom.

出版信息

Cell. 2006 Apr 7;125(1):19-21. doi: 10.1016/j.cell.2006.03.020.

DOI:10.1016/j.cell.2006.03.020

PMID:16615884

Abstract

In the early stages of meiosis, all the telomeres in the cell attach to the nuclear envelope and gather near the centrosome. This polarized chromosomal array is known as the bouquet, as the clustered telomeres resemble the gathered stems of a floral arrangement. In this issue of Cell, Chikashige et al. (2006) provide intriguing clues about the molecular details underlying this conserved meiotic event.

摘要

在减数分裂的早期阶段，细胞中的所有端粒都附着在核膜上，并聚集在中心体附近。这种极化的染色体排列被称为花束，因为聚集的端粒类似于插花中聚集在一起的茎。在本期《细胞》杂志中，Chikashige等人（2006年）提供了关于这一保守减数分裂事件背后分子细节的有趣线索。