Yu Jeong Jin, Yeom Hee Hyun, Chung Sochung, Park Youngshin, Lee Dong Hwan
Department of Pediatrics, Konkuk University School of Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
J Pediatr. 2006 Mar;148(3):321-5. doi: 10.1016/j.jpeds.2005.10.042.
To measure left atrial (LA) diameter in normotensive, overweight children and to determine the variables that independently influence LA diameters.
A cross-sectional study on 22 overweight children (age, 13.40 +/- 1.22 years) and 18 control children (age, 13.40 +/- 2.19 years) was performed. LA diameter, left ventricular (LV) geometry, and LV systolic/diastolic function were measured through echocardiography. Data were compared between the two groups. Multiple regression analysis, with LA diameter as dependent variable, was conducted.
In the overweight group, LV diastolic dimension, LV mass index, peak S, S/D ratio, Am, maximal LA diameter (34.1 mm vs 25.4 mm), middle LA diameter (26.9 mm vs 18.1 mm), and minimal LA diameter (22.5 mm vs 16.1 mm) were increased and Em/Am ratio was decreased. In multiple regression analysis, body mass index (R(2) = 0.7040, 0.7085, 0.7406 in respective maximal, middle, and minimal LA diameter) and systolic blood pressure (R(2) = 0.0540, 0.0477, 0.030 in respective maximal, middle, and minimal LA diameter) were significant independent correlates of all three measures of LA diameter.
LA diameter in normotensive overweight children is increased. Body mass index and systolic blood pressure were significant correlates of LA diameter.
测量血压正常的超重儿童的左心房（LA）直径，并确定独立影响LA直径的变量。
对22名超重儿童（年龄13.40±1.22岁）和18名对照儿童（年龄13.40±2.19岁）进行了横断面研究。通过超声心动图测量LA直径、左心室（LV）几何结构和LV收缩/舒张功能。对两组数据进行比较。以LA直径为因变量进行多元回归分析。
超重组中，LV舒张末期内径、LV质量指数、峰值S、S/D比值、Am、最大LA直径（34.1mm对25.4mm）、中间LA直径（26.9mm对18.1mm）和最小LA直径（22.5mm对16.1mm）增加，Em/Am比值降低。在多元回归分析中，体重指数（最大、中间和最小LA直径的R²分别为0.7040、0.7085、0.7406）和收缩压（最大、中间和最小LA直径的R²分别为0.0540、0.0477、0.030）是所有三种LA直径测量值的显著独立相关因素。
血压正常的超重儿童的LA直径增加。体重指数和收缩压是LA直径的显著相关因素。
