Johnson Susan R, Marion Alicia A, Vrchoticky Teri, Emmanuel Patricia J, Lujan-Zilbermann Jorge
Division of Infectious Diseases, Department of Pediatrics, University of South Florida College of Medicine, Tampa, 33606, USA.
J Pediatr. 2006 Mar;148(3):386-8. doi: 10.1016/j.jpeds.2005.11.034.
We present 2 cases of Cushing syndrome with secondary adrenal insufficiency from concomitant use of ritonavir and inhaled corticosteroids in children with human immunodeficiency virus infection. These cases highlight the need for special consideration when treatment with an inhaled/intranasal corticosteroid is indicated in children receiving antiretroviral therapy.
我们报告了2例人类免疫缺陷病毒感染儿童因同时使用利托那韦和吸入性糖皮质激素而导致库欣综合征并继发肾上腺功能不全的病例。这些病例凸显了在接受抗逆转录病毒治疗的儿童中如需使用吸入/鼻内糖皮质激素进行治疗时,需要特别考虑的必要性。