Rettew David C, Doyle Alicia C, Kwan Monica, Stanger Catherine, Hudziak James J
Department of Psychiatry, University of Vermont College of Medicine, 89 Beaumont Avenue, Given Building Room B227, Burlington, VT 05405, USA.
J Anxiety Disord. 2006;20(7):931-45. doi: 10.1016/j.janxdis.2006.02.002. Epub 2006 Apr 17.
Studies of individuals with an increased tendency to experience negative emotions such as fear, sadness, and anger have documented links between this temperamental trait and anxiety disorders. There exists debate, however, concerning the degree to which high levels of a temperamental trait are a necessary and/or sufficient component of a DSM diagnosis. In this study, receiver operating characteristic (ROC) analyses assessed the relations between levels of harm avoidance (HA) and generalized anxiety disorder (GAD) diagnoses in 334 children and their parents. Analyses revealed HA scores to be highly predictive of GAD diagnoses in children (AUC=.791, P<.001) and adults (AUC=.818, P<.001). However, there were many individuals with high HA scores who did not qualify for a GAD diagnosis. These findings suggest that while there are strong associations between HA and GAD, high levels of HA are neither necessary nor sufficient in the formation of clinically significant anxiety symptoms.
对那些更容易体验恐惧、悲伤和愤怒等负面情绪的个体进行的研究，记录了这种气质性特质与焦虑症之间的联系。然而，对于气质性特质的高水平在多大程度上是《精神疾病诊断与统计手册》（DSM）诊断的必要和/或充分组成部分，存在争议。在本研究中，接受者操作特征（ROC）分析评估了334名儿童及其父母的回避伤害（HA）水平与广泛性焦虑症（GAD）诊断之间的关系。分析显示，HA分数对儿童（曲线下面积[AUC]=0.791，P<0.001）和成人（AUC=0.818，P<0.001）的GAD诊断具有高度预测性。然而，有许多HA分数高的个体不符合GAD诊断标准。这些发现表明，虽然HA与GAD之间存在很强的关联，但高水平的HA在临床上显著焦虑症状的形成中既不是必要的也不是充分的。
