Yegane R-A, Salehi N-A, Ghaseminegad A, Bahrami F, Bashashati M, Ahmadi M, Hojjati M
Loqman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Iran.
Eur J Vasc Endovasc Surg. 2006 Oct;32(4):397-401. doi: 10.1016/j.ejvs.2006.02.014. Epub 2006 Apr 17.
To assess the complications related to intravenous drug abuse.
Prospective study.
Intravenous drug abusers (IVDAs) with vascular complications were assessed.
Sixty-two patients presented with swelling and tenderness in the groin, and 3 patients with similar lesions in the cubital fossa. Infected pseudoaneurysms and deep vein thrombosis (DVTs) were diagnosed in 41 and 31 patients respectively (27 patients had both lesions). In patients with infected pseudoaneurysms, 9 patients underwent excision with early revascularization and 32 patients underwent ligation without revascularization. For all patients with femoral vein thrombosis ligation and excision was performed. 4 patients with pure DVTs were managed conservatively. Disabling claudication occurred in 6 patients. Four of them underwent late revascularization with an acceptable outcome.
Ligation without revascularization is the appropriate treatment of infected pseudoaneurysms in IVDAs. Late revascularization is of great importance in patients with disabling claudication after treatment of addiction. Pure septic DVTs can be managed conservatively.
评估与静脉药物滥用相关的并发症。
前瞻性研究。
对有血管并发症的静脉药物滥用者(IVDA)进行评估。
62例患者腹股沟出现肿胀和压痛,3例患者肘窝有类似病变。分别在41例和31例患者中诊断出感染性假性动脉瘤和深静脉血栓形成(DVT)(27例患者同时有这两种病变)。在感染性假性动脉瘤患者中,9例患者接受了切除并早期进行血管重建,32例患者接受了结扎且未进行血管重建。对所有股静脉血栓形成患者进行了结扎和切除。4例单纯DVT患者采用保守治疗。6例患者出现致残性跛行。其中4例患者接受了晚期血管重建,结果尚可。
对于IVDA患者的感染性假性动脉瘤,不进行血管重建的结扎是合适的治疗方法。在成瘾治疗后出现致残性跛行的患者中,晚期血管重建非常重要。单纯感染性DVT可采用保守治疗。