van Kan Jan A L
Wageningen University, Laboratory of Phytopathology, Binnenhaven 5, 6709 PD Wageningen, The Netherlands.
Trends Plant Sci. 2006 May;11(5):247-53. doi: 10.1016/j.tplants.2006.03.005. Epub 2006 Apr 17.
Necrotrophic plant pathogens have received an increasing amount of attention over the past decade. Initially considered to invade their hosts in a rather unsophisticated manner, necrotrophs are now known to use subtle mechanisms to subdue host plants. The gray mould pathogen Botrytis cinerea is one of the most comprehensively studied necrotrophic fungal plant pathogens. The genome sequences of two strains have been determined. Targeted mutagenesis studies are unraveling the roles played in the infection process by a variety of B. cinerea genes that are required for penetration, host cell killing, plant tissue decomposition or signaling. Our increasing understanding of the tools used by a necrotrophic fungal pathogen to invade plants will be instrumental to designing rational strategies for disease control.
在过去十年中，坏死营养型植物病原体受到了越来越多的关注。坏死营养型病原体最初被认为是以一种相当简单的方式侵入宿主，现在已知它们会利用微妙的机制来征服宿主植物。灰霉病菌是研究最为全面的坏死营养型真菌植物病原体之一。已测定了两个菌株的基因组序列。靶向诱变研究正在揭示灰霉病菌的各种基因在感染过程中所起的作用，这些基因是穿透、杀死宿主细胞、分解植物组织或信号传导所必需的。我们对坏死营养型真菌病原体用于侵入植物的工具的了解不断增加，这将有助于设计合理的疾病控制策略。
