Sato Takeo, Tsuru Tsunehisa, Hagiwara Kiyofumi, Miyashita Kazuhisa, Matsuno Hiroaki, Goto Atsuo, Oritsu Masaru, Hamanaka Teruhiko, Akiyama Osamu
Department of Allergy and Rheumatology, Japanese Red Cross Medical Center, Tokyo.
Intern Med. 2006;45(6):363-8. doi: 10.2169/internalmedicine.45.1521. Epub 2006 Apr 17.
A 45-year-old woman had bleary eyes and recurrent episodes of fever and arthritis in the knees and ankles. The patient had anterior uveitis, negative findings of the tuberculin test, and an increased serum lysozyme level, but bilateral hilar lymphadenopathy (BHL) was absent. During the course of her disease, the serum calcium and angiotensin-converting enzyme levels gradually increased to above the normal level, and the patient was clinically diagnosed as having sarcoidosis. The clinical features of arthritis were typical of those of Löfgrens syndrome although BHL and erythema nodosum were absent. The patient was successfully treated with 15 mg/day of prednisolone.
一名45岁女性出现眼睛模糊，以及膝盖和脚踝反复发热和关节炎发作。该患者患有前葡萄膜炎，结核菌素试验结果为阴性，血清溶菌酶水平升高，但无双侧肺门淋巴结肿大（BHL）。在疾病过程中，血清钙和血管紧张素转换酶水平逐渐升高至正常水平以上，该患者临床诊断为结节病。尽管没有BHL和结节性红斑，但关节炎的临床特征是 Löfgren 综合征的典型特征。该患者接受每日15毫克泼尼松龙治疗，效果良好。
