Sequeira W, Stinar D
Arch Intern Med. 1986 Jan;146(1):125-7.
The serum angiotensin-converting enzyme (SACE) level is elevated in 75% of patients with sarcoidosis and often is associated with disease activity. In an attempt to correlate the SACE level with sarcoid arthritis, we did a retrospective chart review of 116 patients with sarcoidosis. Of the 24 patients who complained of arthritis, five were excluded from the study because they were receiving corticosteroids, SACE levels were not determined, or another cause for their arthritis was found. The mean SACE levels were 65 units/mL for the patients with acute arthritis and 51 units/mL for the patients with chronic arthritis. Levels of SACE may be helpful in the differential diagnosis of patients with "seronegative polyarthritis."
75%的结节病患者血清血管紧张素转换酶（SACE）水平升高，且常与疾病活动相关。为了将SACE水平与结节病关节炎相关联，我们对116例结节病患者进行了回顾性病历审查。在24例主诉有关节炎的患者中，5例被排除在研究之外，原因是他们正在接受皮质类固醇治疗、未测定SACE水平或发现了其关节炎的其他病因。急性关节炎患者的平均SACE水平为65单位/毫升，慢性关节炎患者为51单位/毫升。SACE水平可能有助于“血清阴性多关节炎”患者的鉴别诊断。
