Zhao Kai-jun, Pu Cun-hai, Guan Zhi-yu
Najing Zhongshan Pharmaceutical Factory, Najing 210012, China.
Zhong Yao Cai. 2006 Feb;29(2):181-4.
To study optimum inclusion process condition for volatile oil with beta-cyclodextrin (beta-CD).
The optimum preparation condition were investigated by orthogonal design. The influence of utilization beta-CD and oil, inclusion temperature and time were studied to determin the utilization ratio of volatile oil and oil-bearing rate.
The optimum preparation conditions were established as: volatile oil: beta-CD was 1:10, the inclusion temperature was 60 degrees C and inclusion time was 3h.
The method is convenient and can he used for mass production.
研究β-环糊精(β-CD)包合挥发油的最佳工艺条件。
采用正交设计法考察最佳制备条件。研究β-CD与油的用量、包合温度和时间对挥发油利用率及含油率的影响。
确定最佳制备条件为:挥发油与β-CD比例为1:10,包合温度为60℃,包合时间为3小时。
该方法简便,可用于大规模生产。