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[小儿感冒舒颗粒中荆芥挥发油β-环糊精包合工艺研究]

[Study on the process of inclusion volatile oil of Herba Schizonepetae with beta-cyclodextrin from xiao'er ganmaoshu granule].

作者信息

Zhao Kai-jun, Pu Cun-hai, Guan Zhi-yu

机构信息

Najing Zhongshan Pharmaceutical Factory, Najing 210012, China.

出版信息

Zhong Yao Cai. 2006 Feb;29(2):181-4.

PMID:16617790
Abstract

OBJECTIVE

To study optimum inclusion process condition for volatile oil with beta-cyclodextrin (beta-CD).

METHODS

The optimum preparation condition were investigated by orthogonal design. The influence of utilization beta-CD and oil, inclusion temperature and time were studied to determin the utilization ratio of volatile oil and oil-bearing rate.

RESULTS

The optimum preparation conditions were established as: volatile oil: beta-CD was 1:10, the inclusion temperature was 60 degrees C and inclusion time was 3h.

CONCLUSION

The method is convenient and can he used for mass production.

摘要

目的

研究β-环糊精（β-CD）包合挥发油的最佳工艺条件。

方法

采用正交设计法考察最佳制备条件。研究β-CD与油的用量、包合温度和时间对挥发油利用率及含油率的影响。

结果

确定最佳制备条件为：挥发油与β-CD比例为1:10，包合温度为60℃，包合时间为3小时。

结论

该方法简便，可用于大规模生产。

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