Kłuciński Piotr, Mazur Bogdan, Kaufman Joanna, Hrycek Antoni, Cieślik Paweł, Martirosian Gayane
Department of Medical Microbiology, Medical University of Silesia, Katowice, Poland.
Int J Occup Med Environ Health. 2005;18(4):327-30.
Workers of x-ray departments are occupationally exposed to long-term low levels of ionizing radiation. The aim of the study was to investigate the influence of occupational exposure of low-level x-ray radiation on immunoglobulin and C-reactive protein (CRP) concentrations in radiology workers.
In the study group of 41 x-ray department workers and the control group composed of 32 persons, immunoglobulins (IgM, IgG, IgA) and CRP concentrations were analyzed. The study group was subdivided by gender and smoking habit.
A significant decrease in IgG level was found in the workers and the female subgroup. The same observation was made when smokers and nonsmokers of both groups were compared. Smoking workers showed lower concentrations of IgA than non-smokers. The remaining results of immunoglobulin and CRP concentrations did not show significant differences.
Occupational exposure to low levels of ionizing radiation is associated with suppressive influence on the immunoglobulin production, especially IgG. In addition, smoking decreases the production of IgA in radiology workers.
放射科工作人员职业性暴露于长期低水平的电离辐射。本研究的目的是调查职业性低水平X射线辐射暴露对放射科工作人员免疫球蛋白和C反应蛋白（CRP）浓度的影响。
在由41名放射科工作人员组成的研究组和由32人组成的对照组中，分析免疫球蛋白（IgM、IgG、IgA）和CRP浓度。研究组按性别和吸烟习惯进行细分。
在工作人员和女性亚组中发现IgG水平显著降低。当比较两组吸烟者和非吸烟者时，也有相同的观察结果。吸烟的工作人员IgA浓度低于非吸烟者。免疫球蛋白和CRP浓度的其余结果未显示出显著差异。
职业性低水平电离辐射暴露与对免疫球蛋白产生的抑制作用有关，尤其是IgG。此外，吸烟会降低放射科工作人员IgA的产生。
