Monden Y
Second Department of Surgery, Tokushima University School of Medicine.
Kyobu Geka. 1991 Dec;44(13):1126-31.
The treatment of thymoma, thymic cancer and thymic germ cell tumor was reviewed in the literature. The major treatment of thymoma is surgery with or without radiation. The chemotherapy for the thymoma is now investigated in the world. CDDP, ADM, VCR, CPA or BLM are usually used, but the most effective combination of these drugs is not known. Thymic cancer is a rarer and more malignant disease than thymoma. Though the postoperative treatment is investigated as well as thymoma, only a few successful cases by chemotherapy have been reported. Chemotherapy (PVB, VAB-6, PEB) for testicular germ cell tumor is also effective for thymic germ cell tumor including seminoma. Though the combination therapy of radiation and surgery has been popular, chemotherapy will be used more frequently for seminoma in future.
文献中对胸腺瘤、胸腺癌和胸腺生殖细胞肿瘤的治疗进行了综述。胸腺瘤的主要治疗方法是手术，可辅以或不辅以放疗。目前全球正在研究胸腺瘤的化疗方法。通常使用顺铂、阿霉素、长春新碱、环磷酰胺或博来霉素，但这些药物的最有效组合尚不清楚。胸腺癌比胸腺瘤更罕见且恶性程度更高。虽然像胸腺瘤一样也在研究其术后治疗，但仅有少数化疗成功的病例报道。用于睾丸生殖细胞肿瘤的化疗（顺铂-长春新碱-博来霉素、长春新碱-阿霉素-顺铂-博来霉素、顺铂-依托泊苷-博来霉素）对包括精原细胞瘤在内的胸腺生殖细胞肿瘤也有效。虽然放疗和手术的联合治疗一直很普遍，但未来化疗在精原细胞瘤治疗中的应用将更加频繁。
