淋巴细胞毒性抗体。HLA抗原关联、疾病关联及家族研究。
Lymphocytotoxic antibodies. HLA antigen associations, disease associations, and family studies.
作者信息
Raum D, Glass D, Soter N A, Stillman J S, Carpenter C B, Schur P H
出版信息
Arthritis Rheum. 1977 May;20(4):933-6. doi: 10.1002/art.1780200405.
Lymphocytotoxic antibodies (LCTAB) were sought in sera of patients with rheumatic diseases and in family members. Patients with SLE and cutaneous necrotizing venulitis and family members of JRA patients had an increased frequency of LCTAB; JRA patients and family members of SLE patients did not. The only association between LCTAB and the HLA phenotype of persons with LCTAB was a decreased frequency of LCTAB in individuals with HLA-B27.
在风湿性疾病患者及其家庭成员的血清中寻找淋巴细胞毒性抗体（LCTAB）。系统性红斑狼疮（SLE）患者、皮肤坏死性静脉炎患者以及幼年类风湿关节炎（JRA）患者的家庭成员中，LCTAB的出现频率增加；JRA患者以及SLE患者的家庭成员中则未出现这种情况。LCTAB与携带LCTAB者的人类白细胞抗原（HLA）表型之间唯一的关联是，HLA - B27个体中LCTAB的出现频率降低。
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