Schocket A L, Kohler P F
Arthritis Rheum. 1979 Oct;22(10):1060-3. doi: 10.1002/art.1780221003.
Sera from patients with systemic lupus erythematosus (SLE) and clinically related diseases were examined for cold-reactive lymphocytotoxic antibodies (LCA). The incidence of LCA was significantly increased in SLE (93%), discoid lupus (50%), and "lupus-like" syndromes associated with congenital complement deficiencies (63%) as compared to normal controls (3%) and patients with drug-induced lupus (11%), mixed connective tissue disease (MCTD) (17%), and necrotizing vasculitis (19%). The diagnostic and pathogenetic implications of these differences are discussed.
对系统性红斑狼疮（SLE）患者及临床相关疾病患者的血清进行了冷反应性淋巴细胞毒性抗体（LCA）检测。与正常对照（3%）、药物性狼疮患者（11%）、混合性结缔组织病（MCTD）患者（17%）和坏死性血管炎患者（19%）相比，SLE（93%）、盘状红斑狼疮（50%）以及与先天性补体缺陷相关的“狼疮样”综合征（63%）中LCA的发生率显著升高。讨论了这些差异在诊断和发病机制方面的意义。
