Christensen Bruce W, Roberts John F, Pozor Malgorzata A, Giguere Steeve, Sells Stephen F, Donahue James M
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA.
J Am Vet Med Assoc. 2006 Apr 15;228(8):1234-9. doi: 10.2460/javma.228.8.1234.
A 4-year-old Thoroughbred mare was evaluated because of placental abnormalities and a retained placental remnant.
Microbial culture of the placenta yielded pure growth of Amycolatopsis spp. Histologic examination of the placenta revealed a focally expanding chorionitis with intralesional gram-positive filamentous bacilli and multifocal allantoic adenomatous hyperplasia on the apposing allantoic surface.
Treatment with lavage and oxytocin resulted in expulsion of the placental remnant within hours of parturition. The mare did not become pregnant again despite multiple breedings. The foal appeared healthy but died of complications during an elective surgical procedure at 7 weeks of age.
To the author's knowledge, all previously confirmed cases of nocardioform placentitis have been in mares bred in the central Kentucky region. Indications that the pathogen in the mare reported here is a different species than that isolated in Kentucky suggest that this is an emerging disease. Mares with nocardioform placentitis usually do not have the same clinical signs as mares with placentitis resulting from an ascending pathogen.
一匹4岁的纯种母马因胎盘异常和胎盘残留接受评估。
胎盘微生物培养结果显示为拟无枝酸菌属的纯培养物。胎盘组织学检查显示有局灶性扩张性绒毛膜炎，病灶内有革兰氏阳性丝状杆菌，相对的尿囊表面有多灶性尿囊腺瘤样增生。
通过冲洗和催产素治疗，在分娩后数小时内排出了胎盘残留。尽管多次配种，这匹母马未再次怀孕。小马驹看似健康，但在7周龄时进行择期手术时死于并发症。
据作者所知，之前所有确诊的诺卡氏菌样胎盘炎病例均发生在肯塔基州中部地区繁育的母马身上。此处报告的母马体内病原体与在肯塔基州分离出的病原体不同，这表明这是一种新出现的疾病。患有诺卡氏菌样胎盘炎的母马通常没有因上行性病原体导致胎盘炎的母马所具有的相同临床症状。
