Kabir Ajran, Lamichhane Bibek, Habib Tasmia, Adams Alexis, El-Sheikh Ali Hossam, Slovis Nathan M, Troedsson Mats H T, Helmy Yosra A
Maxwell H. Gluck Equine Research Center, Department of Veterinary Science, Martin-Gatton College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40546, USA.
College of Veterinary Medicine, Lincoln Memorial University, Harrogate, TN 37752, USA.
Antibiotics (Basel). 2024 Jul 29;13(8):713. doi: 10.3390/antibiotics13080713.
The equine industry holds substantial economic importance not only in the USA but worldwide. The occurrence of various infectious bacterial diseases in horses can lead to severe health issues, economic losses, and restrictions on horse movement and trade. Effective management and control of these diseases are therefore crucial for the growth and sustainability of the equine industry. While antibiotics constitute the primary treatment strategy for any bacterial infections in horses, developing resistance to clinically important antibiotics poses significant challenges to equine health and welfare. The adverse effects of antimicrobial overuse and the escalating threat of resistance underscore the critical importance of antimicrobial stewardship within the equine industry. There is limited information on the epidemiology of antimicrobial-resistant bacterial infections in horses. In this comprehensive review, we focus on the history and types of antimicrobials used in horses and provide recommendations for combating drug-resistant bacterial infections in horses. This review also highlights the epidemiology of antimicrobial resistance (AMR) in horses, emphasizing the public health significance and transmission dynamics between horses and other animals within a One Health framework. By fostering responsible practices and innovative control measures, we can better help the equine industry combat the pressing threat of AMR and thus safeguard equine as well as public health.
马术产业不仅在美国，而且在全球都具有重大的经济意义。马匹中各种传染性细菌疾病的发生会导致严重的健康问题、经济损失以及马匹移动和贸易受限。因此，有效管理和控制这些疾病对于马术产业的发展和可持续性至关重要。虽然抗生素是治疗马匹任何细菌感染的主要策略，但对临床上重要的抗生素产生耐药性给马匹的健康和福利带来了重大挑战。抗菌药物过度使用的不良影响以及耐药性威胁的不断升级凸显了马术产业中抗菌药物管理的至关重要性。关于马匹中抗菌药物耐药细菌感染的流行病学信息有限。在这篇全面综述中，我们聚焦于马匹使用的抗菌药物的历史和类型，并为对抗马匹耐药细菌感染提供建议。本综述还强调了马匹中抗菌药物耐药性（AMR）的流行病学，强调了在“同一健康”框架下马匹与其他动物之间的公共卫生意义和传播动态。通过倡导负责任的做法和创新的控制措施，我们可以更好地帮助马术产业应对AMR的紧迫威胁，从而保障马匹以及公众健康。
