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使用PROMOGRAN*基质(一种蛋白酶调节基质)对深部组织缺损(包括肿瘤切除术后暴露的骨骼)进行伤口预处理。

Wound conditioning of a deep tissue defect including exposed bone after tumour excision using PROMOGRAN* Matrix, a protease-modulating matrix.

作者信息

Tausche Anne-Kathrin, Sebastian Günther

机构信息

Section of Internal Medicine, Department of Rheumatology, University Clinic Carl Gustav Carus, Dresden University of Technology, Fetscherstrasse 74, D-01307 Dresden, Germany.

出版信息

Int Wound J. 2005 Sep;2(3):253-7. doi: 10.1111/j.1742-4801.2005.00120.x.

DOI:10.1111/j.1742-4801.2005.00120.x
PMID:16618330
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7951749/
Abstract

A case study reporting on the successful treatment of a patient affected by a basal cell carcinoma is submitted. Because the carcinoma had infiltrated deeply, a wide excision was necessary, including the removal of bone tissue. The deep tissue defect was treated with PROMOGRAN* Matrix, a protease-modulating matrix, to promote granulation and ensure that the skin graft do survive and heal successfully. In this case study, a rapid development of granulation tissue on the exposed surface of the bone was observed. The benefits of the dressing enabled a successful split-thickness skin grafting to be carried out which gave very good aesthetic and functional results.

摘要

本文提交了一份关于成功治疗一名基底细胞癌患者的病例报告。由于癌症已深度浸润,需要进行广泛切除,包括去除骨组织。深部组织缺损采用PROMOGRAN*基质(一种蛋白酶调节基质)进行治疗,以促进肉芽组织生长,并确保皮肤移植能够成功存活和愈合。在本病例报告中,观察到骨暴露表面肉芽组织迅速生长。该敷料的优点使得能够成功进行中厚皮片移植,获得了非常好的美学和功能效果。

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本文引用的文献

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Int Wound J. 2004 Apr;1(1):81-4. doi: 10.1111/j.1742-481x.2004.0002.x.
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Promogran and complex surgical lesions: a case report.普济痔疮栓与复杂手术创面:一例报告
J Wound Care. 2004 Jun;13(6):237-9. doi: 10.12968/jowc.2004.13.6.26628.
3
The influence of a biomaterial on the closure of a marginal hard tissue defect adjacent to implants. An experimental study in the dog.生物材料对种植体周围边缘硬组织缺损封闭的影响。一项在犬类动物身上的实验研究。
Clin Oral Implants Res. 2004 Jun;15(3):285-92. doi: 10.1046/j.1600-0501.2003.01008.x.
4
[Treatment of recalcitrant wounds with autologous epidermal equivalents. After excision of multiple cylindromas of the scalp].[用自体表皮替代物治疗顽固性伤口。头皮多发性圆柱瘤切除术后]
Hautarzt. 2004 Mar;55(3):296-300. doi: 10.1007/s00105-003-0637-8.
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The subsets of keratinocytes responsible for covering open wounds in neonatal rat skin.负责覆盖新生大鼠皮肤开放性伤口的角质形成细胞亚群。
Cell Tissue Res. 2004 Feb;315(2):187-95. doi: 10.1007/s00441-003-0823-0. Epub 2003 Dec 4.
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