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使用PROMOGRAN*基质(一种蛋白酶调节基质)对深部组织缺损(包括肿瘤切除术后暴露的骨骼)进行伤口预处理。

Wound conditioning of a deep tissue defect including exposed bone after tumour excision using PROMOGRAN* Matrix, a protease-modulating matrix.

作者信息

Tausche Anne-Kathrin, Sebastian Günther

机构信息

Section of Internal Medicine, Department of Rheumatology, University Clinic Carl Gustav Carus, Dresden University of Technology, Fetscherstrasse 74, D-01307 Dresden, Germany.

出版信息

Int Wound J. 2005 Sep;2(3):253-7. doi: 10.1111/j.1742-4801.2005.00120.x.

Abstract

A case study reporting on the successful treatment of a patient affected by a basal cell carcinoma is submitted. Because the carcinoma had infiltrated deeply, a wide excision was necessary, including the removal of bone tissue. The deep tissue defect was treated with PROMOGRAN* Matrix, a protease-modulating matrix, to promote granulation and ensure that the skin graft do survive and heal successfully. In this case study, a rapid development of granulation tissue on the exposed surface of the bone was observed. The benefits of the dressing enabled a successful split-thickness skin grafting to be carried out which gave very good aesthetic and functional results.

摘要

本文提交了一份关于成功治疗一名基底细胞癌患者的病例报告。由于癌症已深度浸润,需要进行广泛切除,包括去除骨组织。深部组织缺损采用PROMOGRAN*基质(一种蛋白酶调节基质)进行治疗,以促进肉芽组织生长,并确保皮肤移植能够成功存活和愈合。在本病例报告中,观察到骨暴露表面肉芽组织迅速生长。该敷料的优点使得能够成功进行中厚皮片移植,获得了非常好的美学和功能效果。

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