Tausche A-K, Richter-Huhn G, Sebastian G
Klinik und Poliklinik für Dermatologie des Universitätsklinikums der TU Dresden.
Hautarzt. 2004 Mar;55(3):296-300. doi: 10.1007/s00105-003-0637-8.
A 63 year old man developed non-healing ulcerations after en-bloc resection of multiple cylindromas of the scalp. After excision and granulation-stimulating local therapy, the wound was covered with mesh grafts from the thighs. He developed widespread tension blisters with superficial ulcerations in the occipital region which did not heal despite adequate topical therapy. We then treated him successfully with EpiDex, a tissue engineered fully differentiated epidermal equivalent derived from keratinocytes of the outer root sheath of plucked anagen hair follicles. We introduce this treatment modality as a non-invasive effective option in treating non-healing ulcers.
一名63岁男性在头皮多个圆柱瘤整块切除术后出现不愈合溃疡。切除并进行促进肉芽生长的局部治疗后，伤口用大腿的网状移植物覆盖。他在枕部出现广泛的张力性水疱并伴有浅表溃疡，尽管进行了充分的局部治疗仍未愈合。然后我们用EpiDex成功治疗了他，EpiDex是一种组织工程化的完全分化的表皮替代物，由生长期拔取的毛囊外根鞘角质形成细胞衍生而来。我们将这种治疗方式作为治疗不愈合溃疡的一种非侵入性有效选择进行介绍。
