Mariuzza Roy A
Center for Advanced Research in Biotechnology, W.M. Keck Laboratory for Structural Biology, University of Maryland Biotechnology Institute, Rockville, 20850, USA.
Immunity. 2006 Apr;24(4):359-61. doi: 10.1016/j.immuni.2006.03.009.
The limited primary antibody repertoire uses multiple mechanisms to account for the large number of potential antigens. In this issue of Immunity, Sethi et al. (2006) describe a new means for expanding the antibody repertoire, whereby a single antibody isomer binds diverse antigens at different regions of the binding site.
有限的初始抗体库利用多种机制来应对大量潜在抗原。在本期《免疫》杂志中，塞蒂等人（2006年）描述了一种扩展抗体库的新方法，即单一抗体异构体在结合位点的不同区域结合多种抗原。
