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儿科医生、家庭医生及其他专科医生针对儿童开具抗哮喘药物的处方模式差异。

Differences in the prescription patterns of anti-asthmatic medications for children by pediatricians, family physicians and physicians of other specialties.

作者信息

Sun Hai-Lun, Kao Yea-Huei, Chou Ming-Chieh, Lu Tsung-Hsueh, Lue Ko-Huang

机构信息

Department of Pediatrics, Chung Shan Medical University Hospital, and Institute of Medicine, Taichung, Taiwan.

出版信息

J Formos Med Assoc. 2006 Apr;105(4):277-83. doi: 10.1016/S0929-6646(09)60118-2.

Abstract

BACKGROUND

Prescription patterns of anti-asthma medications in children vary among doctors in different disciplines and settings, and may reflect differences in treatment outcome. The purpose of this study was to analyze the prescribing patterns of anti-asthma drugs by pediatricians, family physicians and other practitioners.

METHODS

Data for a total of 225,537 anti-asthma prescriptions were collected from the National Health Insurance Research Database for the period from January 1, 2002 to March 31, 2002. These medications included inhaled and oral adrenergics, inhaled and oral corticosteroids, xanthine derivatives, and leukotriene receptor antagonists prescribed by general pediatricians, family physicians and physicians in other disciplines.

RESULTS

Oral beta2-agonist was the most commonly prescribed drug used as monotherapy, with prescription rates of 70.4%, 46.9% and 58.0% by pediatricians, family physicians and other physicians, respectively. A xanthine derivative was the next most commonly prescribed monotherapy. Oral corticosteroid combined with oral beta2-agonist, followed by oral beta2-agonist combined with a xanthine derivative were the two most commonly prescribed dual-agent combined therapies by all three physician categories. The prescription rate for inhaled corticosteroid monotherapy was 7.8% by pediatricians, 5.6% by family physicians, and 8.0% by other physicians. The prescription rate for inhaled adrenergic was the highest in family physicians (14.9%), followed by the other physicians (7.2%), and was lowest in pediatricians (3.1%).

CONCLUSION

Pediatricians and family physicians appeared to share similar opinions on the medical management of children with asthma in that both most commonly prescribed oral beta2-agonists and xanthine derivatives, either alone or in combination. Family physicians were least likely to prescribe an inhaled corticosteroid and most likely to prescribe an inhaled adrenergic agent.

摘要

背景

不同学科和环境的医生在儿童抗哮喘药物的处方模式上存在差异,这可能反映出治疗结果的不同。本研究的目的是分析儿科医生、家庭医生和其他从业者的抗哮喘药物处方模式。

方法

从国家健康保险研究数据库中收集了2002年1月1日至2002年3月31日期间总共225537份抗哮喘处方的数据。这些药物包括普通儿科医生、家庭医生和其他学科医生开具的吸入和口服肾上腺素能药物、吸入和口服皮质类固醇、黄嘌呤衍生物以及白三烯受体拮抗剂。

结果

口服β2-激动剂是最常用的单药治疗药物,儿科医生、家庭医生和其他医生的处方率分别为70.4%、46.9%和58.0%。黄嘌呤衍生物是其次最常用的单药治疗药物。口服皮质类固醇联合口服β2-激动剂,其次是口服β2-激动剂联合黄嘌呤衍生物,是所有三类医生最常用的两种联合治疗药物。儿科医生吸入皮质类固醇单药治疗的处方率为7.8%,家庭医生为5.6%,其他医生为8.0%。家庭医生吸入肾上腺素能药物的处方率最高(14.9%),其次是其他医生(7.2%),儿科医生最低(3.1%)。

结论

儿科医生和家庭医生在哮喘儿童的药物治疗方面似乎有相似的观点,即两者最常单独或联合开具口服β2-激动剂和黄嘌呤衍生物。家庭医生最不可能开具吸入皮质类固醇,最可能开具吸入肾上腺素能药物。

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