Yagisawa Mizuho, Ishitoya Junichi, Tsukuda Mamoru
Department of Biology and Function in the Head and Neck, Graduate School of Medicine, Yokohama City University, Japan.
Acta Otolaryngol. 2006 Mar;126(3):277-81. doi: 10.1080/00016480500316746.
We have reported a non-neoplastic, heterogeneous, hemorrhagic lesion of the maxillary sinus characterized by a mixture of dilated vessels, hemorrhage and fibrin exudation. This lesion should be distinguished from hemangioma and hematoma. We propose the name "hematoma-like mass of the maxillary sinus" for this disease, based on its histological characteristics.
To describe the clinicopathological characteristics of a non-neoplastic, heterogeneous, hemorrhagic lesion of the maxillary sinus associated with mucosal swelling and bone destruction.
This was a retrospective review of six patients who were treated surgically for masses and met the following criteria: (i) CT demonstrated an expanding unilateral maxillary lesion, with thinning or destruction of the surrounding bony tissue; (ii) MRI demonstrated a heterogeneous mass; (iii) macroscopically, a mass with a hemorrhagic and heterogeneous appearance was observed; and (iv) histologically, a non-neoplastic tissue with mucosal hemorrhage was observed.
The clinical features of this disease, such as a mass expanding from the maxillary sinus with bone destruction, resembled those of maxillary carcinoma. However, CT and MRI provided sufficient information to differentiate this condition from malignancy. Resection was straightforward due to a firm capsule. Characteristic histological findings were a mixture of dilated vessels, hemorrhage and fibrin exudation.
我们报告了一例上颌窦非肿瘤性、异质性、出血性病变，其特征为扩张血管、出血和纤维蛋白渗出物混合存在。该病变应与血管瘤和血肿相鉴别。基于其组织学特征，我们为此疾病提出“上颌窦血肿样肿物”这一名称。
描述一种与黏膜肿胀和骨质破坏相关的上颌窦非肿瘤性、异质性、出血性病变的临床病理特征。
对6例因肿物接受手术治疗且符合以下标准的患者进行回顾性研究：（i）CT显示单侧上颌病变扩大，周围骨质组织变薄或破坏；（ii）MRI显示肿物异质性；（iii）肉眼观察到一个外观出血且异质性的肿物；（iv）组织学观察到一个伴有黏膜出血的非肿瘤性组织。
该疾病的临床特征，如肿物从上颌窦扩展并伴有骨质破坏，类似于上颌癌。然而，CT和MRI提供了足够信息以将此情况与恶性肿瘤区分开来。由于有坚实的包膜，切除操作较为简单。特征性组织学表现为扩张血管、出血和纤维蛋白渗出物混合存在。
