Even-Tov Ella, Niv A, Kraus M, Nash Michael
Department of Otolaryngology-Head & Neck Surgery, Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel.
Acta Otolaryngol. 2006 Mar;126(3):334-6. doi: 10.1080/00016480500388992.
This report describes the case of an elderly, diabetic man who developed acute suppurative parotitis with abscess formation. The causative agent of parotid abscess was Candida albicans, which is an unusual cause of salivary gland pathology. The parotid gland is the salivary gland most commonly affected by inflammation. Acute parotitis occurs most often in elderly patients who are debilitated by systemic disease or are in a state of dehydration following major surgical procedures. Despite the high prevalence of oral candida carriage, there have been few previous reports of candida sialoadenitis in the literature. This is due to the toxicity of saliva to fungi under normal conditions. The diagnosis of candidiasis in our patient was made by culturing the purulent discharge from Stensen's duct and by culture of the pus obtained at surgical drainage of the abscess. After incision and drainage, the patient was treated with intravenous and then oral fluconazole for a total of 4 weeks with complete resolution of his condition. This case is interesting in light of recent and ongoing investigations of salivary proteins as potential new antifungal agents.
本报告描述了一名老年糖尿病男性患者，他患上了伴有脓肿形成的急性化脓性腮腺炎。腮腺脓肿的病原体是白色念珠菌，这是唾液腺病理的一种不常见病因。腮腺是最常受炎症影响的唾液腺。急性腮腺炎最常发生在因全身性疾病而虚弱或在大手术后处于脱水状态的老年患者中。尽管口腔念珠菌携带率很高，但此前文献中关于念珠菌涎腺炎的报道很少。这是因为在正常情况下唾液对真菌有毒性。我们患者的念珠菌病诊断是通过对斯滕森导管的脓性分泌物进行培养以及对脓肿手术引流时获取的脓液进行培养来确定的。切开引流后，患者接受了静脉注射然后口服氟康唑治疗，总共治疗了4周，病情完全缓解。鉴于最近对唾液蛋白作为潜在新型抗真菌剂的持续研究，该病例很有意思。
