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下颌骨牵张成骨手术治疗上气道梗阻:幼儿长期定量研究结果

Relief of upper airway obstruction with mandibular distraction surgery: Long-term quantitative results in young children.

作者信息

Lin Sandra Y, Halbower Ann C, Tunkel David E, Vanderkolk Craig

机构信息

Department of Otolaryngology-Head & Neck Surgery, The Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.

出版信息

Arch Otolaryngol Head Neck Surg. 2006 Apr;132(4):437-41. doi: 10.1001/archotol.132.4.437.

DOI:10.1001/archotol.132.4.437
PMID:16618914
Abstract

OBJECTIVE

To evaluate the long-term benefits of mandibular distraction on sleep-related upper airway obstruction in young children with mandibular hypoplasia.

DESIGN

Cross-sectional study. Subjects were examined for sleep-disordered breathing using medical history, physical examination results, and a written questionnaire. Subjects underwent standard overnight polysomnography, during which measures of sleep-disordered breathing were collected.

SETTING

Tertiary care hospital.

PATIENTS

Five children with upper airway obstruction from craniofacial anomalies treated with mandibular distraction, with a minimum follow-up of 12 months.

MAIN OUTCOME MEASURES

Apnea-hypopnea index, oxygen saturation nadir, and peak end-tidal carbon dioxide value.

RESULTS

Of the 5 children, 3 were cured of upper airway obstruction as documented by polysomnography, with an apnea-hypopnea index of less than 1.5 and no snoring. The fourth child had primary snoring without apnea. The fifth child had severe obstructive sleep apnea, with an apnea-hypopnea index of 20.2.

CONCLUSIONS

Most children who undergo mandibular distraction for upper airway obstruction associated with mandibular hypoplasia demonstrate significant clinical improvement of obstructive sleep apnea. However, those children who continue to have symptoms of sleep-disordered breathing after surgery should undergo polysomnography for evaluation of persistent obstructive sleep apnea.

摘要

目的

评估下颌骨牵张成骨术对下颌骨发育不全幼儿睡眠相关上气道阻塞的长期疗效。

设计

横断面研究。通过病史、体格检查结果和书面问卷对受试者进行睡眠呼吸障碍检查。受试者接受标准的夜间多导睡眠监测,期间收集睡眠呼吸障碍的相关指标。

地点

三级医疗中心。

患者

5例因颅面畸形导致上气道阻塞并接受下颌骨牵张成骨术治疗的儿童,最小随访时间为12个月。

主要观察指标

呼吸暂停低通气指数、最低血氧饱和度和呼气末二氧化碳峰值。

结果

5例儿童中,3例经多导睡眠监测证实上气道阻塞治愈,呼吸暂停低通气指数小于1.5且无打鼾。第4例儿童仅有原发性打鼾,无呼吸暂停。第5例儿童患有严重阻塞性睡眠呼吸暂停,呼吸暂停低通气指数为20.2。

结论

大多数因下颌骨发育不全导致上气道阻塞而接受下颌骨牵张成骨术的儿童,阻塞性睡眠呼吸暂停症状有显著临床改善。然而,术后仍有睡眠呼吸障碍症状的儿童应接受多导睡眠监测,以评估是否存在持续性阻塞性睡眠呼吸暂停。

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