D'Ascanio L, Cavuto C, Martinelli M, Salvinelli F
Department of Otolaryngology, School of Medicine, Campus Bio-Medico, University of Rome, Rome, Italy.
Minerva Stomatol. 2006 Apr;55(4):223-8.
Congenital agenesis of major salivary glands is a rare entity with unclear etiopathogenesis, sometimes presenting in a bilateral form. This pathologic condition is often diagnosed with delay because of the poor clinical presentation. Only bilateral forms of parotid aplasia are responsible of such a severe lack of saliva causing dental caries, periodontal diseases, ascending sialadenitis and candidosis. In most cases, the aplasia involves more than a single major salivary gland and is occasionally associated with other developmental anomalies of the head-neck region. A case is presented in which an aplasia of the right parotid gland is associated with hypoplasia of the thyroid's right lobe and homolateral angioma of the homolateral cheek. We report the clinical and radiological findings in our patient and a review of the diagnostic imaging approach in such anomalies.
大唾液腺先天性发育不全是一种病因不明的罕见病症，有时呈双侧发病形式。由于临床表现不典型，这种病理状况常常被延迟诊断。只有双侧腮腺发育不全才会导致如此严重的唾液缺乏，进而引发龋齿、牙周疾病、上行性涎腺炎和念珠菌病。在大多数情况下，发育不全涉及不止一个大唾液腺，偶尔还与头颈部区域的其他发育异常相关。本文报告了一例右侧腮腺发育不全合并右侧甲状腺叶发育不全及同侧颊部血管瘤的病例。我们介绍了该患者的临床和影像学检查结果，并对这类异常的诊断性影像学检查方法进行了综述。
