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[光学相干断层扫描在斯塔加特病中的应用]

[Optical coherence tomography in Stargardt's dystrophy].

作者信息

Samsel Agnieszka, Dróbecka-Brydak Ewa, Brydak-Godowska Joanna, Ciszewska Joanna, Kecik Dariusz

机构信息

Z Katedry i Kliniki Okulistyki Akademii Medycznej w Warszawie.

出版信息

Klin Oczna. 2005;107(10-12):668-71.

Abstract

Stargardt's disease is one of the central retinal dystrophies with its onset in first two decades of life presenting gradual decrease in visual acuity and typical features in fluorescein angiography. The aim of the study was to evaluate the macular area in patients with diagnosed Stargardt's disease with the use of optical coherence tomography. 11 patients (22 eyes) were enrolled to the study. OCT examination revealed characteristic similar features of macular images in all patients. They included decreased thickness of the retina, most prominent in foveola, and changes in external retinal layers: lack of photoreceptors and nuclear external layer and changes in retinal pigment epithelium. Because of typical features in macular appearance, optical coherence tomography may become a useful tool for confirming diagnosis of Stargardt's disease.

摘要

斯塔加特病是一种中心性视网膜营养不良,发病于生命的前二十年,表现为视力逐渐下降以及荧光素血管造影的典型特征。本研究的目的是利用光学相干断层扫描技术评估已确诊斯塔加特病患者的黄斑区。11名患者(22只眼)纳入本研究。光学相干断层扫描检查显示所有患者黄斑图像均有相似的特征性表现。包括视网膜厚度降低,在中心小凹最为明显,以及视网膜外层的改变:光感受器和外层神经核层缺失,视网膜色素上皮改变。由于黄斑外观具有典型特征,光学相干断层扫描可能成为确诊斯塔加特病的有用工具。

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