Jiang Xian-zhou, Zhang Jian-wei, Xu Zhi-shun
Department of Urology, Qilu Hospital of Shandong University, Jinan 250012, China.
Zhonghua Wai Ke Za Zhi. 2006 Jan 15;44(2):108-10.
To investigate the diagnoses and treatment of interstitial cystitis (IC).
The clinical data of 16 IC patients were analyzed respectively. The patients with urinary frequency, urgency, suprapubic pain and chronic pelvic pain. They were misdiagnosed as chronic cystitis, pelvic inflammation, endometriosis, cystophthisis and urethral syndrome, and were diagnosed finally by the means of pathology or cystoscopy. Among the 16 patients, 4 cases had the operation of ileal reservoir, Two cases had sigmoid-cysto-plasty, and 10 cases had drug treatment. The methods of IC diagnosis and treatment were discussed with the review of literature.
The pelvic ache disappeared completely in 4 cases after the operation of ileal reservoir; Two cases after cystoplasty felt lightly discomfortable in perineum occasionally, and their bladder capacity was above 350 ml, no recurrence after operation having been found after follow-up for 24 months and 33 months; Ten cases treated with non-operative treatment improved obviously, with the O'Leary-Sant IC symptom index and IC problem index decreased from 15.4 +/- 4.1, 9.4 +/- 2.7 to 4.1 +/- 2.1 and 5.1 +/- 3.9, respectively.
Sufficient attention should be paid to the diagnosis and differential diagnosis of IC; Early diagnosis and therapeutic alliance with manifold measures can relieve the patients' symptom and improve the quality of life.
探讨间质性膀胱炎（IC）的诊断与治疗。
对16例IC患者的临床资料进行分析。患者有尿频、尿急、耻骨上区疼痛及慢性盆腔疼痛症状。曾被误诊为慢性膀胱炎、盆腔炎、子宫内膜异位症、膀胱结核及尿道综合征，最终经病理或膀胱镜检查确诊。16例患者中，4例行回肠膀胱术，2例行乙状结肠膀胱扩大术，10例行药物治疗。结合文献复习对IC的诊断和治疗方法进行讨论。
4例行回肠膀胱术的患者术后盆腔疼痛完全消失；2例行膀胱扩大术的患者术后会阴部偶尔有轻度不适，膀胱容量均大于350ml，随访24个月和33个月均未复发；10例行非手术治疗的患者症状明显改善，O'Leary-Sant IC症状指数和IC问题指数分别从15.4±4.1、9.4±2.7降至4.1±2.1和5.1±3.9。
应充分重视IC的诊断与鉴别诊断；早期诊断并采取多种措施联合治疗可缓解患者症状，提高生活质量。
