Strayer Scott M, Slawson David C, Shaughnessy Allen F
University of Virginia Health System, Department of Family Medicine, P.O. Box 800729, Charlottesville, Virginia USA 22908-0729, USA.
J Am Med Inform Assoc. 2006 Jul-Aug;13(4):396-8. doi: 10.1197/jamia.M2045. Epub 2006 Apr 18.
This case study examined the recent withdrawal of valdecoxib to determine the timeliness of updates in commonly used information sources used by healthcare professionals. The method included assembling a purposive sample of 15 drug reference and warning systems that were then systematically monitored for several months after the withdrawal of valdecoxib to determine the time to update this information. These information sources were classified and described qualitatively. A time to diffusion curve was plotted and the average number of days to report the drug withdrawal or update reference databases was calculated. Only 2 of 15 information systems reported the drug withdrawal on the actual date of the FDA announcement. Institutional electronic textbooks took an average of 109.8 days (+/-14 days) to report the withdrawal. In addition, one pharma-sponsored dissemination source (Peerview Press) had not updated their information as of this publication.
本案例研究调查了近期伐地昔布撤市的情况，以确定医疗保健专业人员常用信息来源更新的及时性。方法包括选取15个药物参考和警示系统组成一个有目的的样本，在伐地昔布撤市后对其进行数月的系统监测，以确定更新此信息的时间。对这些信息来源进行了分类和定性描述。绘制了传播时间曲线，并计算了报告药物撤市或更新参考数据库的平均天数。15个信息系统中只有2个在FDA宣布撤市的实际日期报告了该药物撤市。机构电子教科书报告撤市平均用时109.8天（±14天）。此外，截至本出版物发布时，一个由制药公司赞助的传播源（同行评审出版社）尚未更新其信息。
