通过磁共振成像（MRI）诊断的乳头佩吉特病

Paget's disease of the nipple diagnosed by MRI.

作者信息

Capobianco Giampiero, Spaliviero Bernardino, Dessole Salvatore, Cherchi Pier Luigi, Marras Vincenzo, Ambrosini Guido, Meloni Francesco, Meloni Giovanni Battista

机构信息

Department of Pharmacology, Gynecology and Obstetrics, University of Sassari, Viale San Pietro 12, Sassari 07100, Italy.

出版信息

Arch Gynecol Obstet. 2006 Aug;274(5):316-8. doi: 10.1007/s00404-006-0160-0. Epub 2006 Apr 19.

DOI:10.1007/s00404-006-0160-0

PMID:16622685

Abstract

BACKGROUND

Paget's disease of the breast is a rare manifestation of breast carcinoma.

CASE REPORT

The patient presented with a red lesion of the left nipple-areola complex. Breast physical examination, ultrasonography and mammography were normal bilaterally. Magnetic resonance imaging (MRI) correctly depicted Paget's disease of the nipple. Before surgery the patient underwent biopsy of the lesion that showed Paget's disease of the breast associated with an underlying ductal carcinoma in situ. The patient underwent left mastectomy and unilateral axillary lymph node dissection. The patient refused the breast-conserving surgery because she was afraid that she could have a recurrence of the carcinoma. Microscopy of the lesion confirmed the MRI diagnosis.

CONCLUSION

MRI was very useful and accurate to diagnose Paget's disease of the breast without palpable mass, ultrasonographic and mammographic findings.

摘要

背景

乳腺佩吉特病是乳腺癌的一种罕见表现形式。

病例报告

患者左侧乳头乳晕复合体出现红色病变。双侧乳房体格检查、超声检查及乳腺X线摄影均正常。磁共振成像（MRI）准确显示了乳头佩吉特病。手术前，患者接受了病变活检，结果显示乳腺佩吉特病合并潜在原位导管癌。患者接受了左侧乳房切除术及单侧腋窝淋巴结清扫术。患者因担心癌症复发而拒绝保乳手术。病变显微镜检查证实了MRI诊断。