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肿瘤学中的全身磁共振成像

Total-body MR-imaging in oncology.

作者信息

Schaefer Juergen F, Schlemmer Heinz-Peter W

机构信息

Department of Diagnostic Radiology, University of Tuebingen, Hoppe- Seyler-Str. 3, 72076, Tuebingen, Germany.

出版信息

Eur Radiol. 2006 Sep;16(9):2000-15. doi: 10.1007/s00330-006-0199-0. Epub 2006 Apr 19.

DOI:10.1007/s00330-006-0199-0
PMID:16622688
Abstract

Although MRI is an effective modality in oncology, state-of-the-art total-body MRI (TB-MRI) in the past was infeasible in the diagnostic work-up, due to the need for repeated examinations with repositioning and separate surface coils to cover all body parts. To overcome this limitation, either a moving table platform in combination with the body-coil or a special designed rolling table platform with one body phased-array coil have been implemented with promising results for both tumor staging and metastases screening. Since 2004, state-of-the-art TB-MR imaging with high spatial resolution has become feasible using a newly developed 1.5 Tesla TB-MRI system with multiple receiver channels. This review gives an overview based on the recent literature as well as our own experience concerning the possibilities, challenges, and limitations of TB-MRI in oncology, emphasizing both oncological staging and early tumor detection in asymptomatic subjects.

摘要

尽管磁共振成像(MRI)在肿瘤学领域是一种有效的检查方式,但过去的先进全身MRI(TB-MRI)在诊断检查中并不可行,因为需要重复检查并重新定位,且要用单独的表面线圈来覆盖身体所有部位。为克服这一局限性,已采用两种方法:一种是结合体线圈的移动检查床平台,另一种是配备单个体相控阵线圈的特殊设计滚动检查床平台,二者在肿瘤分期和转移灶筛查方面均取得了良好效果。自2004年以来,使用新开发的具有多个接收通道的1.5特斯拉TB-MRI系统,实现具有高空间分辨率的先进TB-MR成像已成为可能。本综述基于近期文献以及我们自身的经验,概述了TB-MRI在肿瘤学中的可能性、挑战和局限性,重点关注肿瘤分期和无症状受试者的早期肿瘤检测。

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