手术及放疗治疗足踝部弥漫性色素沉着绒毛结节性滑膜炎
Diffuse pigmented villonodular synovitis of the foot and ankle treated with surgery and radiotherapy.
作者信息
Lee M, Mahroof S, Pringle J, Short S C, Briggs T W R, Cannon S R
机构信息
Bone and Soft Tissue Tumour Unit, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, London, UK.
出版信息
Int Orthop. 2005 Dec;29(6):403-5. doi: 10.1007/s00264-005-0004-8.
Abstract
We followed up seven patients with histologically confirmed diffuse pigmented villonodular synovitis in a prospective study between 1992 ans 2001. The mean age at diagnosis was 30.7 years. The patients underwent synovectomy, followed by radiotherapy with a total dose of 35 Gy in 20 fractions. In all cases, the excision was considered incomplete when examined histologically. At an average follow up of 24 (18-36) months, six patients reported better function and reduced levels of pain. One patient remained symptomatic but did not have a recurrence. We conclude that a combined approach to a primary pigmented villonodular synovitis of the foot and ankle may reduce the risk of recurrence without functional impairment.
摘要
在1992年至2001年的一项前瞻性研究中，我们对7例经组织学确诊为弥漫性色素沉着绒毛结节性滑膜炎的患者进行了随访。诊断时的平均年龄为30.7岁。患者接受了滑膜切除术，随后进行放疗，总剂量为35 Gy，分20次给予。在所有病例中，组织学检查时切除均被认为不完全。平均随访24（18 - 36）个月时，6例患者报告功能改善且疼痛程度减轻。1例患者仍有症状，但未复发。我们得出结论，对于足踝原发性色素沉着绒毛结节性滑膜炎采用联合治疗方法可能会降低复发风险且不造成功能损害。
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