Raffaghello Lizzia, Pistoia Vito
Laboratory of Oncology, G Gaslini Institute, Largo Gerolamo Gaslini 5, 16147 Genova, Italy.
Expert Rev Neurother. 2006 Apr;6(4):509-18. doi: 10.1586/14737175.6.4.509.
Neuroblastoma is a neuroectodermal tumor of childhood with poor prognosis and low survival in patients with advanced-stage disease who respond to conventional therapies but unfortunately, often present relapse. Therefore, the search for novel therapeutic strategies is warranted and represents the objective of many investigators. Among the new, innovative approaches, immunotherapy has attracted much interest. However, until recently, little information was available about the immunogenicity of human neuroblastoma.
神经母细胞瘤是一种儿童期神经外胚层肿瘤，晚期疾病患者预后较差且生存率低，这些患者对传统疗法有反应，但不幸的是，常出现复发。因此，有必要寻找新的治疗策略，这也是许多研究人员的目标。在新的创新方法中，免疫疗法引起了广泛关注。然而，直到最近，关于人类神经母细胞瘤免疫原性的信息还很少。
