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血液透析动静脉内瘘狭窄:评估与治疗

Stenosis in hemodialysis arteriovenous fistula: evaluation and treatment.

作者信息

Campos Rodrigo P, Do Nascimento Marcelo M, Chula Domingos C, Do Nascimento Daniel E, Riella Miguel C

机构信息

Evangelic Faculty of Parana, Evangelic University Hospital of Curitiba, Curitiba, Brazil.

出版信息

Hemodial Int. 2006 Apr;10(2):152-61. doi: 10.1111/j.1542-4758.2006.00087.x.

Abstract

Vascular access complications are one of the main causes associated with an increase in morbidity and mortality in stage 5 chronic kidney disease patients. The arteriovenous fistula is regarded as the vascular access of choice for hemodialysis (HD) because of its superior patency and lower complication rates. Stenosis is considered the major cause of dysfunction of arteriovenous fistula. Despite the relatively low thrombosis rates of arteriovenous fistula, surveillance programs are necessary for detection of stenosis. We report a case of a HD patient who had never achieved an adequate Kt/V since the start of maintenance HD. During the investigation, abnormal findings were found on physical examination of the fistula, in addition to an alteration in intra-access pressure (IAP) measurements. A venous stenosis was diagnosed by Doppler ultrasound and then promptly treated with percutaneous transluminal angioplasty. The purpose of the discussion is to highlight the peculiarities of arteriovenous fistulae, methods of surveillance, including physical examination, IAP, recirculation, and measurements of blood flow, and the importance of the correction procedures for the stenosis.

摘要

血管通路并发症是导致5期慢性肾脏病患者发病率和死亡率增加的主要原因之一。动静脉内瘘因其通畅性好、并发症发生率低,被视为血液透析(HD)的首选血管通路。狭窄被认为是动静脉内瘘功能障碍的主要原因。尽管动静脉内瘘的血栓形成率相对较低,但仍需要监测程序来检测狭窄。我们报告一例维持性血液透析患者,自开始维持性血液透析以来,其Kt/V从未达到足够水平。在检查过程中,除了内瘘压力(IAP)测量值改变外,在内瘘体格检查中还发现了异常情况。通过多普勒超声诊断为静脉狭窄,随后立即进行经皮腔内血管成形术治疗。讨论的目的是强调动静脉内瘘的特点、监测方法,包括体格检查、IAP、再循环和血流量测量,以及狭窄矫正程序的重要性。

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