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移民与艾滋病毒感染对结核病低流行地区结核病发病率的影响。

Impact of immigration and HIV infection on tuberculosis incidence in an area of low tuberculosis prevalence.

作者信息

Baussano I, Bugiani M, Gregori D, Pasqualini C, Demicheli V, Merletti F

机构信息

Cancer Epidemiology Unit, CPO Piemonte, CeRMS, University of Turin, Italy.

出版信息

Epidemiol Infect. 2006 Dec;134(6):1353-9. doi: 10.1017/S0950268806006261. Epub 2006 Apr 20.

Abstract

The aim of this study is to assess the effects of immigration from countries with a high prevalence of tuberculosis (HPCs), of HIV/AIDS prevalence, and the ageing of the indigenous population, on tuberculosis distribution in a low-prevalence area (LPCs), the Piedmont Region of Italy. Tuberculosis incidence and HIV cases were identified by linking records from the surveillance systems. Overall, 640 tuberculosis cases were identified and crude annual incidence was found to be 17.3/100000. The incidence rate ratio for HIV infection as a risk factor for tuberculosis (11.4 and 51.9 among individuals from HPCs and LPCs respectively) was greater than that for immigration from HPCs (6.7 and 30.9 among HIV+ and HIV- individuals). Immigration accounted for a larger number of incident cases [population attributable risk % (PAR %): 31.8 and 52.8% among HIV+ and HIV- individuals] than did HIV infection (PAR %: 5.4 and 11.1% among individuals from HPCs and LPCs). Efforts should be made to identify and treat young immigrants from HPCs.

摘要

本研究旨在评估来自结核病高流行国家(HPCs)的移民、艾滋病毒/艾滋病流行情况以及本土人口老龄化对意大利皮埃蒙特地区这个低流行地区(LPCs)结核病分布的影响。通过关联监测系统的记录来确定结核病发病率和艾滋病毒病例。总体而言,共确定了640例结核病病例,粗年发病率为17.3/10万。艾滋病毒感染作为结核病危险因素的发病率比(分别来自HPCs和LPCs的个体中为11.4和51.9)高于来自HPCs的移民(艾滋病毒阳性和阴性个体中分别为6.7和30.9)。与艾滋病毒感染相比,移民导致的新发病例数更多(艾滋病毒阳性和阴性个体中的人群归因风险百分比(PAR%)分别为31.8%和52.8%),而艾滋病毒感染导致的PAR%在来自HPCs和LPCs的个体中分别为5.4%和11.1%。应努力识别和治疗来自HPCs的年轻移民。

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