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[猫丘脑腹外侧核部分损伤时大脑半球运动皮质的代偿过程]

[Compensatory processes in the motor cortex of the cerebral hemispheres in partial damage to the ventrolateral thalamic nucleus in the cat].

作者信息

Chernyshevskaia I A, Sidorov B M

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1991 Sep-Oct;41(5):1050-8.

PMID:1662435
Abstract

In cats alimentary instrumental reflex was elaborated of lever transference by the right forepaw in a definite zone--prior to and after the electrolytic damage of the left ventrolateral thalamic nucleus. It was found that even a slight damage led to disturbance of precise movements mostly expressed in the first two weeks; after that gradual normalization of the motor reactions took place. At morphological study of various pyramidal neurones and also satellite and general glia in the zone of presentation of the ventrolateral nucleus in the cerebral cortex a hypertrophy was discovered of the pyramidal cells and their processes in III and V layers, accompanied by active reaction of various glia forms. Morphometric processing and statistic analysis of the obtained data showed the dominance of structural compensatory changes observed in the cortex on the side of VL damage.

摘要

在猫身上,通过右前爪在特定区域进行杠杆转移来建立食物性工具反射,实验分别在左侧丘脑腹外侧核电解损伤之前和之后进行。结果发现,即使是轻微损伤也会导致精确运动受到干扰,这种干扰在最初两周最为明显;之后运动反应逐渐恢复正常。在对大脑皮层腹外侧核投射区的各种锥体神经元以及卫星细胞和普通胶质细胞进行形态学研究时,发现第三和第五层的锥体细胞及其突起出现肥大,同时伴有各种胶质细胞形态的活跃反应。对所得数据进行形态测量处理和统计分析表明,在腹外侧核损伤侧的皮层中观察到结构代偿性变化占主导地位。

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