Kaczynski J, Hansson G, Norkrans G, Wallerstedt S
Department of Medicine, Ostra Hospital, Göteborg, Sweden.
Acta Oncol. 1991;30(7):811-3. doi: 10.3109/02841869109091826.
The incidence of primary carcinoma of the liver in Sweden has been reported to increase. In order to study the role of chronic hepatitis B virus (HBV) infection for liver cancer development 40 cases with hepatocellular carcinoma (HCC) were examined for the presence of HBV surface antigen and HBV core antigen in the cancer and in the surrounding non-neoplastic liver tissue. It was not possible to demonstrate a single case with tissue HBV antigen, indicating that HBV plays a minor role in the etiology of HCC in Sweden and thus does not seem to be responsible for the increasing incidence of this cancer.
据报道，瑞典原发性肝癌的发病率呈上升趋势。为了研究慢性乙型肝炎病毒（HBV）感染在肝癌发生中的作用，对40例肝细胞癌（HCC）患者的癌组织及周围非肿瘤性肝组织进行了HBV表面抗原和HBV核心抗原检测。未发现一例组织中有HBV抗原，这表明HBV在瑞典HCC的病因中作用较小，因此似乎不是该癌症发病率上升的原因。
