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颞骨化学感受器瘤的放射治疗结果

Results of radiotherapy in chemodectoma of the temporal bone.

作者信息

Skołyszewski J, Korzeniowski S, Pszon J

机构信息

Department of Radiation Oncology, Instytut im. M. Skłodowskiej-Curie, Kraków, Poland.

出版信息

Acta Oncol. 1991;30(7):847-9. doi: 10.3109/02841869109091833.

DOI:10.3109/02841869109091833
PMID:1662524
Abstract

Between 1958 and 1986, twenty-four patients with chemodectoma of the temporal bone received radiation therapy at the Center of Oncology in Cracow. In 22 patients incomplete excision of the tumor had been performed at other hospitals before admission for radiotherapy. Two patients had biopsy only. Three patients had early stage tumors without bone destruction or cranial nerve palsy and 21 patients had advanced tumors at presentation. Three patients treated between 1958 and 1967 received orthovoltage 250 V irradiation, 20 patients received 60Co teletherapy, and one patient received a combination of photon and electron therapy. Tumor doses ranged from 30 Gy to 60 Gy, given in 2-2.5 Gy fractions, 5 times weekly. There were no serious acute or late complications. Long-term local control was achieved in 23 patients with follow-up ranging from 16 months to 21.5 years (median 87 months). Only one patient had locally uncontrolled tumor along with lung and cervical node metastases. Irradiation appeared to be an effective and well tolerated method of treatment in chemodectoma of the temporal bone.

摘要

1958年至1986年间,24例颞骨化学感受器瘤患者在克拉科夫肿瘤中心接受了放射治疗。22例患者在入院接受放射治疗前,曾在其他医院接受过肿瘤不完全切除。2例患者仅接受了活检。3例患者为早期肿瘤,无骨质破坏或颅神经麻痹,21例患者就诊时为晚期肿瘤。1958年至1967年间接受治疗的3例患者接受了250千伏的常压放疗,20例患者接受了60钴远距离治疗,1例患者接受了光子和电子联合治疗。肿瘤剂量范围为30 Gy至60 Gy,分2 - 2.5 Gy分次给予,每周5次。未出现严重的急性或晚期并发症。23例患者获得了长期局部控制,随访时间为16个月至21.5年(中位时间87个月)。只有1例患者局部肿瘤未得到控制,并伴有肺和颈部淋巴结转移。放射治疗似乎是颞骨化学感受器瘤一种有效且耐受性良好的治疗方法。

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